ADHD theories still need to take more on board: Serotonin and pre-executive variablity

A commentary on "A dynamic developmental theory of Attention-Deficit/Hyperactivity Disorder (ADHD) predominantly hyperactive/ impulsive and combined subtypes"

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correcting the relationship between tonic and burst firing modes in dopamine neurons may help normalise stimulus-reinforcement gradients and contingent behaviour in attention-deficit/hyperactivity disorder (adhd) children. but appropriate evaluations of stimuli for developing adaptive plans and controlling impulsivity will not occur without moderating the gain-like functions of serotonin. the “dynamic theory” correctly highlights the need to account for variability in adhd. the dysmaturation of pre-executive information processing is proposed as an explanation. at the core of the article by sagvolden and colleagues there is a set of data that throws light on an aspect of the adhd phenomenon. but one asks if the authors are a measure too brave to generalise so broadly from the unusually steep reinforcement gradients reported for the human condition and an animal model to the syndrome as a whole.
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Fakultät / Institut:
Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie und Psychotherapie des Kindes- und Jugendalters
Dewey Dezimal-Klassifikation:
600 Technik, Medizin, angewandte Wissenschaften » 610 Medizin und Gesundheit » 610 Medizin und Gesundheit
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E-Publikationen / Dokument veröffentlicht
Dateien geändert am:
Behavioral and Brain Sciences, Vol. 28 (2005) ; no. 3, p. 438 / DOI:10.1017/S0140525X0533007X Pick It!