In many industries structural change through E-Commerce is challenging firms to re-align their strategies as well as re-engineer their business processes with new competitive environments while taking advantage of technological opportunities. This article presents E-MEMO, a method for multi-perspective enterprise modelling with special emphasis on processes and technologies for E-ommerce. It serves to analyse and design corporate information systems that are balanced with a company’s E-Commerce strategy and its organization. E-MEMO offers specific languages for modelling strategies, business processes, and related resources. In addition to that, it provides a library of reference models including strategy networks to guide strategic planning and models of business processes. In order to further support the implementation of information systems a transformation has been defined that allows for generating workflow schemata from business process models.