This thesis analyzes in what respect human biosignals are suitable for communication among man and machine. An exemplary communication system is presented which provides the operation of a computer mouse by electro-oculographical signals (EOG) and head movements of the user. Special eyeglasses with integrated electrodes, amplifiers and acceleration sensors measure the biosignals and transfer them to computer-aided signal processing. In order to discuss here the relationship between 'biosignals' and 'information' it is necessary to define precisely these central quantities of man-machine communication. The applied information model with its five hierarchical levels statistics, syntax, semantics, pragmatics, and apobetics*, and empirically derived laws about information achieves this goal. Therefore, only under certain conditions the energetic-material biosignals of the individual are information carriers concurrently. It is compellingly concluded from the model that information can only be transmitted if the user of the man-machine system has voluntarily influenceable biosignals. Individually dependent, many bioelectric signals (among other biosignals) fulfil this condition: EOG, EMG and EEG signals, e. g.. Therefore, they are potentially suitable for communication in various man-machine systems. The operational man-machine system is based on the principles of the above information model and so exemplarily confirms the general statements. Obviously, biological signals for realistic man-machine communication must generally correspond to this information model. Keywords: biosignal, communication, man-machine System, information, EOG signal, head movement, computer mouse (* Derived from Greek 'apobeinon' = result, success, conclusion).