Brand, Matthias; Kalbe, Elke; Kracht, Lutz W.; Riebel, Ulrich; Münch, Jürgen; Kessler, Josef; Markowitsch, Hans J.:
Organic and psychogenic factors leading to executive dysfunctions in a patient suffering from surgery of a colloid cyst of the Foramen of Monro
2004
In: Neurocase: The Neural Basis of Cognition, Jg. 10 (2004), Heft 6, S. 420 - 425
Artikel/Aufsatz in Zeitschrift / Fach: Angewandte Kognitionswissenschaften
Fakultät für Ingenieurwissenschaften » Informatik und Angewandte Kognitionswissenschaft
Titel:
Organic and psychogenic factors leading to executive dysfunctions in a patient suffering from surgery of a colloid cyst of the Foramen of Monro
Autor(in):
Brand, Matthias im Online-Personal- und -Vorlesungsverzeichnis LSF anzeigen; Kalbe, Elke; Kracht, Lutz W.; Riebel, Ulrich; Münch, Jürgen; Kessler, Josef; Markowitsch, Hans J.
Erscheinungsjahr:
2004
Erschienen in:
Neurocase: The Neural Basis of Cognition, Jg. 10 (2004), Heft 6, S. 420 - 425

Abstract:

The authors report a 41-year-old female patient who had suffered from colloid cyst of the Foramen of Monro. After surgical intervention in which the cyst was completely removed, her hydrocephalus decreased to normal ventricle size measured by MRI. However, the patient became depressive and reported vast difficulties in everyday life decision-making. An examination twenty months after surgery indicated psychiatric symptoms and abnormalities in personality. Neuropsychological investigation revealed average to above average performance in anterograde memory, attention, information processing, and intelligence. In contrast, the patient was severely impaired in decision-making, complex executive functions, and social cognition. In 18F-2-fluoro-2-deoxy-D-glucose (18FDG-PET) hypometabolism in bilateral dorsolateral prefrontal cortex, cingulate cortex and left fusiform gyrus was observed. The authors conclude that in this case decision-making deficits and executive dysfunctions are influenced by both organic and psychogenic factors.