Kaiser, Markus; Wetzel, Stefan; Kumar, K.; Waldmann, Herbert:

Biology-inspired synthesis of compound libraries

In: Cellular and molecular life sciences, Jg. 65 (2008) ; 7/8, S. 1186-1201
ISSN: 1420-682X
Zeitschriftenaufsatz / Fach: Biologie
Biologically active small molecules represent
the basis for chemical biology applications in
which small molecules are used as chemical tools to
probe biological processes. In this report, we review
two approaches to design and synthesize compound
libraries for biological screenings, i.e., diversity-oriented
synthesis (DOS) and biology-oriented synthesis