Solid phase total synthesis of the 3-amino-6-hydroxy-2-piperidone (Ahp) cyclodepsipeptide and protease inhibitor Symplocamide A.

In: Chemical communications : ChemComm, (2010) ; Nr. 46, S. 8857-8859
ISSN: 0022-4936, 0009-241X, 1359-7345
Zeitschriftenaufsatz / Fach: Biologie
Fakultät für Biologie
The solid phase total synthesis of the marine cyanobacterial
Ahp-cyclodepsipeptide Symplocamide A is reported as a model
for a general route for the synthesis of tailor-made non-covalent
serine protease inhibitors.