Kaiser, Markus; Ottmann, Christian:
The First Small-Molecule Inhibitor of 14-3-3s: Modulating the Master Regulator
2010
In: ChemBioChem : a European journal of chemical biology, Jg. 11 (2010), Heft 15, S. 2085 - 2087
Artikel/Aufsatz in Zeitschrift2010Biologie
Fakultät für Biologie
Titel:
The First Small-Molecule Inhibitor of 14-3-3s: Modulating the Master Regulator
Autor(in):
Kaiser, MarkusLSF; Ottmann, Christian
Erscheinungsjahr
2010
WWW URL

Abstract:

Adapting the adapter: The identification, synthesis and cellular activity of the first 14-3-3 protein–protein interaction inhibitor have recently been reported. This success opens up new possibilities for small-molecule modulation of the biology of these important adapter proteins with the potential for new therapeutic approaches.