Brand, Matthias; Borsutzky, Sabine; Fujiwara, Esther; Markowitsch, Hans J.:

Susceptibility to false memories in patients with ACoA aneurysm. Empfaenglichkeit fuer Gedaechtnistaeuschungen bei Patienten mit ACoA-Aneurysma.

In: Neuropsychologia : an international journal., Jg. 48 (2010) ; Nr. 10, S. 2811-2823
ISSN: 0028-3932
Zeitschriftenaufsatz / Fach: Angewandte Kognitionswissenschaften
Fakultät für Ingenieurwissenschaften » Informatik und Angewandte Kognitionswissenschaft
Abstract:
Investigated the susceptibility of patients with anterior communicating artery (ACoA) aneurysm to a range of false-memory phenomena. Participants included 18 patients with rupture and repair of an aneurysm of the ACoA aged 33-58 years and 17 healthy controls aged 35-77 years. All participants underwent neuropsychological tests assessing intelligence (Leistungspruefsystem, LPS), short-term memory (Wechsler Gedaechtnistest, WMS-R), verbal learning and verbal long-term memory (Memo-Test, M-T), visual long-term memory (as measured by a delayed recall of the Rey-Osterreith Complex Figure), attention (German version of the Trail Making Test Part A, TMT-A; Farbe-Wort-Interferenztest, FWIT; Aufmerksamkeits-Belastungs-Test, d2), executive functions (using a modified version of the Wisconsin Card Sorting Test, WCST), susceptibility to interference (Farbe-Wort-Interferenztest, FWIT), mental flexibility (using a German version of the Trail Making Test Part B, TMT-B), verbal fluency (FAS-Test), and visuospatial abilities (Rey-Osterreith Figure). In addition, the Confabulation Interview (taken from the Testbatterie zur Erfassung von Konfabulationstendenzen, TEKT), the German version of the Mini-Mental-State-Examination (MMSE), the Deese-Roediger-McDermott (DRM) paradigm, and a new version of the mirror-reading task were administered to assess confabulation, orientation in time and place, false memories such as intrusions and false recognition in anterograde memory, and false memory in procedural memory, respectively. Results showed that more provoked confabulations and false recognition in mirror reading were observed in ACoA patients than in healthy controls. False recall/false recognition in the DRM paradigm was observed to be similar in patients and controls. It is suggested that rupture of ACoA aneurysms leads to an increased susceptibility to a subset of false-memory types. The results are concluded to confirm the assumption that provoked confabulations can be disassociated from false recall and false recognition in verbal-learning tasks representing a distinct entity of false-memory phenomena