Zimmermann, Sonja; Menzel, Christoph M.; Berner, Zsolt; Eckhardt, Jörg-Detlef; Stüben, Doris; Alt, Friedrich; Messerschmidt, Jürgen; Taraschewski, Horst; Sures, Bernd:

Trace analysis of platinum in biological samples: a comparison between sector field ICP-MS and adsorptive cathodic stripping voltammetry following different digestion procedures.

In: Analytica chimica acta : an international journal devoted to all branches of analytical chemistry., Jg. 439 (2001) ; Nr. 2, S. 203-209
ISSN: 0003-2670, 0378-4304
Zeitschriftenaufsatz / Fach: Biologie
A study was carried out to analyse Pt trace levels in fish liver and mussel soft tissue, using two different analytical techniques. Sector field inductively coupled plasma mass spectrometry (SF-ICP-MS) combined with microwave digestion was compared with adsorptive cathodic stripping voltammetry (ACSV) following high pressure ashing (HPA). A microwave digestion procedure for animal tissue was developed, using HNO3 and H2O2. The procedural detection limit of Pt with SF-ICP-MS in combination with this digestion procedure was 2.4 ng/l in the solution. The subsequent detection limit considering 300 mg liver tissue (wet weight) was found to be 200 pg/g Pt. In comparison, the detection power of ACSV after HPA digestion was about 20 times more sensitive. The higher procedural detection limit of the ICP-MS-based method is due to the high dilution necessary to reduce acid concentration. Nevertheless, the results of both analytical methods differed between 16 and 30% for Pt concentrations below 1 ng/g, and were almost identical (2–10% deviation) above this value. The Pt levels in the animal tissues analysed ranged between 0.1 and 2.3 ng/g.