Knoelker, Hans Joachim; Boese, Roland; Hitzemann, Rainer:
Imidazole derivatives. Part II. Synthesis of imidazo[1,2-a]pyridin-5-ones.
1989
In: Heterocycles, Jg. 29 (1989), Heft 8, S. 1551 - 1558
Artikel/Aufsatz in Zeitschrift / Fach: Chemie
Titel:
Imidazole derivatives. Part II. Synthesis of imidazo[1,2-a]pyridin-5-ones.
Autor(in):
Knoelker, Hans Joachim; Boese, Roland im Online-Personal- und -Vorlesungsverzeichnis LSF anzeigen; Hitzemann, Rainer
Erscheinungsjahr
1989
Erschienen in:
Heterocycles, Jg. 29 (1989), Heft 8, S. 1551 - 1558
ISSN

Abstract:

The reaction of 2-phenacylimidazole with acetylenic esters RC.tplbond.CCO2Me (R = H, CO2Me) provides imidazo[1,2-a]pyridin-5-ones I (R = same, R1 = H) by an one-pot procedure. Methylation of I (R1 = H) with CH2N2 gave N-Me derivs. I (R1 = Me). The structure of I (R = CO2Me, R1 = Me) was proved by x-ray crystallog.