Heberling, Katharina Maria:
Effekte sexueller Stimulation auf immunologische Parameter bei Männern
Duisburg-Essen, 2005
2005Dissertation
MedizinMedizinische Fakultät » Universitätsklinikum Essen » Institut für Medizinische Psychologie und Verhaltensimmunbiologie
Titel:
Effekte sexueller Stimulation auf immunologische Parameter bei Männern
Autor*in:
Heberling, Katharina Maria
Akademische Betreuung:
Petersenn, StephanUDE
LSF ID
47416
Sonstiges
der Hochschule zugeordnete*r Autor*in
Erscheinungsort:
Duisburg-Essen
Erscheinungsjahr:
2005
Umfang:
105 S. : graph. Darst.
DuEPublico 1 ID
Signatur der UB:
Notiz:
Duisburg, Essen, Univ., Diss., 2005

Abstract:

OBJECTIVE: Sexual arousal and orgasm induce an increase in sympathetic activity as well as in catecholamine and prolactin plasma concentrations. However, the effects of sexual arousal and orgasm on immune functions in man are unknown. Thus, this study investigated the effects of masturbation-induced orgasm on lymphocyte circulation and cytokine production in healthy young males. METHODS: In a crossover design, 11volunteers completed an experimental condition in which they were asked to masturbate until orgasm and to participate in a control condition without sexual activity. Blood was drawn continuously for determination of endocrine parameters. In addition, leukocyte and lymphocyte subsets were analyzed via flow cytometry, and the production of lipopolysaccharide-induced interleukin 6 and tumor necrosis factor alpha was measured before and then 5 and 45 min after the orgasm. RESULTS: The results confirmed transient increases in adrenaline and prolactin plasma concentrations. Sexual arousal and orgasm increased the absolute number of leukocytes, in particular natural killer cells (CD3-CD16+CD56+), in the peripheral blood. In contrast, T cell (CD3+) and B cell (CD3-CD20+) subpopulations as well as the production of interleukin 6 and tumor necrosins factor alpha remained unaffected by sexual activity. CONCLUSION: These findings demonstrate that components of the innate immune system are activated by sexual arousal and orgasm.