C2-symmetric metacyclophanes: a possible alternative to o,o'-bridged binaphthyls.

In: Angewandte Chemie, International Edition, Jg. 46 (2007) ; Nr. 23, S. 4397-4399
ISSN: 1433-7851
Zeitschriftenaufsatz / Fach: Chemie
The trick with the chiral clamp: In metacyclophanes such as (P)-2 it is possible to stabilize one chiral conformation by means of a chiral clamp so effectively that at room temp. only this conformation is present. This conformation resembles that of a o,o'-bridged binaphthyls (for example (P)-1). New binaphthyl alternatives are thus made accessible.