Nijs, R.; Verkruijsse, H.d.; Harder, S.; Van der Kerk, A.c.h.t.m.; Brandsma, L.:

A peculiar reaction of aminoallenes with aromatic and heteroaromatic aldehydes.

In: Synthetic Communications, Jg. 21 (1991) ; Nr. 5, S. 653-656
ISSN: 0039-7911
Zeitschriftenaufsatz / Fach: Chemie
Abstract:
Addn. of allenic amines H2C:C:CHNR2 (R2N = Me2N, morpholino) to a soln. of an arom. or heteroarom. aldehyde, RCH:O, and LiBr in THF followed by treatment of the reaction mixt. with a small amt. of acetic acid at elevated temps. affords the aldehydes RCH:C(CH2NR2)CHO in reasonable yields.