Effects of organometal(loid) compounds on neuronal ion channels: Possible sites for neurotoxicity.
A review on the targets of neurotoxicity of methylated arsenicals and on the mechanisms involved. Evaluations of neurotoxic potency of hazardous substances with an in vivo expression system (Xenopus laevis oocytes) and arsenical effects on transmitter-operated ion channels are presented. Neuronal ion channels as targets for org. arsenicals are considered.
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