Quantitative near infrared spectrometry used for the determination of the content of sennosides in a phytogenic matrix.
In: Pharmazie (Pharmazie), Jg. 52 (1997) ; Nr. 12, S. 931-937
Zeitschriftenaufsatz / Fach: Chemie
The sennoside content of a drug gained from Senna plants can be detd. directly by NIR-spectrometry by measuring the original products in diffuse reflection without further sample prepn. This however requires a previous calibration with stds. the concns. of which have to be detd. by an adequate ref. method. It was shown that HPLC is suitable for this purpose.