Jasper, Christian; Schrader, Thomas; Panitzky, Jens; Klarner, Frank-Gerrit:

Selective complexation of N-alkylpyridinium salts: Recognition of NAD+ in water.

In: Angewandte Chemie, International Edition, Jg. 41 (2002) ; Nr. 8, S. 1355-1358
ISSN: 1433-7851
Zeitschriftenaufsatz / Fach: Chemie
A mol. clip made of two naphthalene side walls and bisphosphonate arms selectively binds to N-alkylpyridinium ions in water. Through the unique potential of this clip to combine p-cation and electrostatic interactions with the hydrophobic effect, the host mol. is able to complex NAD+ (NAD; see picture) efficiently in aq. soln.