Selective complexation of N-alkylpyridinium salts: Recognition of NAD+ in water.
A mol. clip made of two naphthalene side walls and bisphosphonate arms selectively binds to N-alkylpyridinium ions in water. Through the unique potential of this clip to combine p-cation and electrostatic interactions with the hydrophobic effect, the host mol. is able to complex NAD+ (NAD; see picture) efficiently in aq. soln.
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