The recognition and binding of monosaccharides to simple, acyclic saccharide receptors, I (B = CH; R1 = H) and (B = N; R1 = Me), which incorporate three pyridine-amide or pyrimidine-amide moieties interconnected by a Ph spacer are discussed. Although these host mols. possess an acyclic structure, they are able to bind effectively to monosaccharides. These types of host mols. provide both hydrogen bonding sites and it-bonds for facilitating stacking interactions and thus participate in three-dimensional recognition of sugars.