Schrader, Thomas:
Towards synthetic adrenaline receptors - strong binding of amino alcohols by bisphosphonates.
1996
In: Angewandte Chemie, International Edition in English, Jg. 35 (1996), Heft 22, S. 2649 - 2651
Artikel/Aufsatz in Zeitschrift1996Chemie
Titel:
Towards synthetic adrenaline receptors - strong binding of amino alcohols by bisphosphonates.
Autor(in):
Schrader, ThomasLSF
Erscheinungsjahr
1996

Abstract:

Using a simple benzylic bisphosphonate as a synthetic receptor for adrenaline derivs., the assocn. consts. between the receptor and biol. important 1,2-amino alcs. were measured using NMR titrns. in DMSO at 20 Deg and compared with the consts. for their resp. amines. The results suggest that the authors have indeed found a basic structural motif for a receptor of 1,2-amino alcs.