In this work, nanocapsules were synthesized from n-butylcyanoacrylat (BCA) and characterized under variation of kind and quantity of the synthesis components. The influences of the quantity variations were interpreted, using a reduced and a complete factorized experimental design. Hereby, the properties of the capsules have been specified, such as width, width distribution, density, wall thickness and morphology of the capsule. For the verification of the construction of the capsules and their characterization different analytical methods have been used, i.e. TGA, TEM, AFM, AUZ and DLS. In addition, Zeta potentials have been measured and taken into consideration.